I wanted to get SystemTap to run on my Fedora Core 6 box, and had problems getting it running. The README says to install the kernel-debuginfo, which I had problems getting going. It turns out I was just being stupid, and didn't run yum properly. All I really had to do was:

% sudo yum install systemtap
% sudo yum --enablerepo=core-debuginfo --enablerepo=updates-debuginfo  install kernel-debuginfo

More information about System Tap is available here.